There are no known allergens in Zenflore. All raw materials used for Zenflore do not contain any allergen listed in the Directive 2007/68/EC and its amendments. The facilities we use to manufacture also ensure that during the production process, raw materials are not exposed to cross-contamination from allergens. One theory is that the vagus nerve – a long, critical nerve extending from the abdomen to the brain – acts as a neural highway for chemicals made in the gut to get to the brain. In other words, chemicals secreted by microbes in the gut could switch genes on and off in the gut lining, affecting the brain. There seems to be a month for just about everything, but did you know that April is stress awareness month? And with it being the school holidays, I definitely know that it has been a little bit more stressful for me. Less busy for sure, but a little more stress than normal with children arguing and so on. Plus, working from home in the school holidays has meant a lot of late nights and then early mornings getting things done, so that I can be with the children in the day.

That was certainly the case for Louise Riis, whose worst bout of insomnia was when she was working as a magazine editor and dealing with a severe illness in the family. B. longum 1714™ altered resting-state neural oscillations, with an increase in theta band power in the frontal and cingulate cortex ( P< 0.05) and a decrease in beta-3 band in the hippocampus, fusiform, and temporal cortex ( P< 0.05), both of which were associated with subjective vitality changes. All groups showed increased social stress after a 4-week intervention without an effect at behavioral level due to small sample numbers. However, only B. longum 1714™ altered neural oscillation after social stress, with increased theta and alpha band power in the frontal and cingulate cortex ( P< 0.05) and supramarginal gyrus ( P< 0.05). DISCUSSION: Yes. ZenfloreⓇ is suitable for children over the age of 3 years. Please consult your healthcare practitioner for further advice. Exciting new research suggests the key to better sleep might be in your gut bacteria. Editor Anna Magee reports on the rise of the new sleepbiotics

Stress is common to all of us at some point, especially in the current climate of the pandemic and all the uncertainty that brings. Recognising the first signs of stress is vital to being able to combat it effectively. These signs include:- Food Supplements are intended to supplement the diet and should not be substituted for a varied diet or healthy lifestyle. Developed by PrecisionBiotics, the new psychobiotic Zenflore, has been clinically proven to reduce the symptoms of everyday stress, including tiredness, low energy, tension headaches and a weakened immune system. We’ve long known of a connection between the stomach and the brain. Butterflies in the stomach and ‘gut-wrenching’ feelings are clear examples of this phenomenon. Information is sent instantly from the gut to the brain via the nervous and immune systems and hormones (the endocrine system).

ZenfloreⓇ contains the unique and highly beneficial strain of bacteria 1714-SerenitasⓇ which goes to work directly where it is needed in the gut. This strain is a member of the Bifidobacterium family and is one of the ‘good’ bacteria inhabiting the gut. It is also contained in breastmilk and is passed to babies at birth to assist in healthy immune system development, thus making it a particularly special strain. It acts in the gut to stimulate the production of mood-boosting serotonin and has shown to increase activity in the areas of the brain associated with emotions, learning, and memory. The specially selected B vitamins contribute to the reduction of stress and fatigue and encourage normal psychological function. Other research has also looked at the effect of prebiotics – that’s foods and supplements that feed the good bacteria in our bodies – and found that they might also have a beneficial effect on sleep. ‘Prebiotics are important because they feed the good bacteria in our guts and help them grow,’ says Dr Murphy.

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Generally, it takes around two months for the average gut to recover from one course of antibiotics and you can improve this recovery time with a gut-friendly diet of probiotics (the healthy bacteria) and prebiotics (which feed the healthy bacteria and help it grow). It was a struggle and I think the worst bout of insomnia I have ever had – for me sleep is directly link to how much stress I am under. When combined with these vitamins, Zenflore helps fight fatigue. In addition, clinical trials have demonstrated that the encapsulated 1714-Serenitas strain reaches the gut alive, giving maximum efficacy. PrecisionBiotics is proud to have Zenflore featured on renowned platforms such as Healthista and ITV’s ‘Save Money: Good Health’ with Sian Williams and Ranj Singh. They explored how people can lead a healthy lifestyle without breaking the bank. Zenflore, with the unique 1714-Serentitas culture and specially selected B vitamins, provides support for your mind and body during busy and demanding times, reduces fatigue and supports mental performance.*

The special 1714-Serenitas culture in Zenflore was discovered and developed by PrecisionBiotics and has been clinically studied in partnership with scientists and clinicians from one of the world's leading centres of research on the microbiome. Zenflore are capsules designed to give support for your mind and body during busy and demanding times. However, in comparison to other neurophysiological studies with the CBG ( 22,23), our study involved repeated exposure to the social stress 4 weeks apart. Indeed, similar changes in theta band activity induced by B. longum 1714™ were observed in the resting-state data (before playing the CBG) of the current study, which correlated with increased vitality. These data suggest that the increase in theta and alpha band power by B. longum 1714™ before the stressor may be to some degree a priming for the stressor and may represent an upregulation of appraisal processes and coping mechanisms in the expectation of being exposed to a similar stressful situation again. Furthermore, lower frontal alpha power has been associated with anxiety ( 39,40). The increased alpha oscillation activity in our study may indicate the inhibition of limbic activity and thereby counter-regulate negative emotions and stress. Taking this argument further, we suggest that in contrast to placebo, B. longum 1714™ reduced participants' stress response and enabled them to manage the increased distress level by upregulating processes appraising stressful events and downregulating negative emotions. Life in the Shilton household has been rather chaotic of late; building work inside and outside of our home, busy weekends with days out and family time mixed in with work commitments as well as the general running of the household and ensuring the boys are looked after and cared for. It doesn’t leave much time left for me. Thankfully I’ve been trialling a new probiotic called Zenflore, which is a completely natural supplement, that helps to reduce the stress hormone cortisol, and to my surprise, it has really worked. What is Zenflore? PrecisionBiotics® are proud to announce Zenflore®, a natural bacterial strain combined with selected B vitamins to provide support for mind and body through life’s daily challenges. Discovered by PrecisionBiotics® at the world-leading APC Microbiome Institute in Cork, the 1714-Serenitas® Bifidobacterium longum culture belongs to a group of bacteria that can be passed from mother to babies at birth. Combined with specially selected B vitamins, this unique strain works to effectively combat mental fatigue and improve mental performance.Prebiotics can be found in many high fibre fruits and vegetables including root vegetables, artichokes, bananas, asparagus, sweet potatoes to name a few, as well as whole grains and legumes. ‘It’s yet another reason to get your five a day.’